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Flexographic Printing for Food-Safe Paper Packaging: Balancing Print Quality and Regulatory Compliance

Master flexographic printing for food packaging. Learn about food-safe inks, migration testing, print quality parameters, and UK/EU regulatory compliance for paper converting operations.

GML UK Technical Team 5 min read Updated: Jan 6, 2026

Introduction: Why Flexographic Printing Dominates Food Packaging

Flexographic printing accounts for approximately 35% of all packaging print globally, with that figure rising to over 50% for food-contact paper applications. The technology's dominance stems from a combination of practical advantages: high-speed production, compatibility with absorbent substrates, and crucially, the availability of food-safe ink systems that meet stringent regulatory requirements.

For paper converters serving the food industry, flexography presents both opportunities and technical challenges. The process demands precise control over ink formulation, substrate interaction, and curing parameters—any deviation can compromise either print quality or food safety compliance.

This guide examines the technical realities of flexographic printing for food packaging, including ink chemistry, migration considerations, print quality optimisation, and the regulatory framework governing food-contact materials in the UK and EU.

Flexographic Printing Fundamentals for Paper Substrates

The Flexo Process Architecture

Flexographic printing operates on a relatively simple principle: a flexible relief plate transfers ink from an anilox roller to the substrate. However, this simplicity masks significant complexity in execution, particularly when printing on paper for food contact applications.

The key components of a flexographic printing unit include:

The Anilox Roller functions as the precision metering device for ink delivery. Ceramic-coated with laser-engraved cells, modern anilox rollers are specified by their cell count (lines per inch or LPI) and cell volume (measured in billion cubic microns per square inch, or BCM). For paper packaging applications, typical specifications range from 300-500 LPI with volumes between 2.5-5.0 BCM, depending on ink type and coverage requirements.

The Plate Cylinder carries the photopolymer printing plate. Plate durometer (hardness, measured on the Shore A scale) significantly affects print quality on paper substrates. Softer plates (25-35 Shore A) conform better to uncoated paper surfaces but may compromise fine detail reproduction. Harder plates (45-55 Shore A) maintain sharper edges but require more precise impression settings.

The Impression Cylinder provides the counter-pressure necessary for ink transfer. Impression settings on paper substrates require careful calibration—excessive pressure causes dot gain and ink strike-through, while insufficient pressure results in incomplete coverage and inconsistent density.

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Anilox Specification Rule of Thumb

For water-based inks on uncoated paper packaging, start with an anilox specification of approximately 400 LPI at 3.5 BCM. Adjust cell volume upward for process colours requiring higher ink film weight, or downward for fine text and line work.]

Ink Transfer Dynamics on Paper

Unlike film substrates where ink remains largely on the surface, paper's porous structure creates a more complex ink-substrate interaction. Ink penetration into the paper matrix affects both print quality (optical density, colour saturation) and functional properties (rub resistance, migration potential).

The rate and depth of ink absorption depends on several factors:

Paper porosity and surface treatment determine initial ink acceptance. Sized or coated papers exhibit reduced penetration, allowing ink to remain closer to the surface where it contributes to optical density. Uncoated papers may absorb a significant proportion of the ink vehicle, requiring higher ink film weights to achieve equivalent colour strength.

Ink viscosity and surface tension influence wetting behaviour and penetration rate. Lower viscosity inks penetrate faster but may cause feathering at image edges. Higher viscosity improves edge definition but can compromise coverage uniformity.

Drying mechanism and speed affect the final ink distribution. Water-based inks rely primarily on absorption and evaporation, while energy-curable systems polymerise in situ, creating a distinct surface layer.

Food-Safe Ink Systems: Chemistry and Compliance

Water-Based Ink Technology

Water-based flexographic inks represent the predominant choice for direct food-contact paper packaging in the UK and EU markets. These inks use water as the primary carrier, with co-solvents (typically alcohols or glycol ethers) to modify drying characteristics and flow properties.

The binder systems in water-based food packaging inks are typically acrylic emulsions or styrene-acrylic copolymers, selected for their low migration potential and film-forming properties. Pigments must be rigorously evaluated for extraction and migration behaviour under conditions representing actual food contact.

Advantages of water-based systems for food contact:

  • Lower potential for migration of volatile organic compounds
  • Established regulatory acceptance under EU 1935/2004 framework
  • Reduced fire risk in production environments
  • Lower environmental impact compared to solvent-based alternatives

Technical limitations to consider:

  • Slower drying characteristics, particularly in humid conditions
  • Sensitivity to pH variations affecting colour consistency
  • Potential for foam formation requiring antifoam additives
  • Print quality limitations compared to UV-curable systems on coated substrates

UV-Curable Ink Systems

UV-curable inks offer superior print quality and production speed but require more rigorous compliance management for food contact applications. The free-radical polymerisation mechanism that enables rapid curing also creates migration risk from unreacted photoinitiators and monomers.

For food packaging applications, low-migration (LM) UV inks are formulated with:

High molecular weight photoinitiators that are effectively bound into the cured ink film, reducing migration potential. Modern polymeric photoinitiators achieve migration levels below 10 ppb for most food types.

Carefully selected monomers and oligomers with high reactivity (ensuring complete cure) and low intrinsic migration potential. Acrylate chemistry dominates, with specific structures selected to optimise the cure/migration balance.

LED-UV systems operating at 385-395nm wavelengths enable lower photoinitiator concentrations compared to mercury arc systems, reducing one significant source of migration risk.

"The shift to LED-UV curing has transformed food packaging printing. We're achieving migration levels that would have been impossible five years ago, while actually improving production speeds."

— Technical Director, UK Packaging Converter

Electron Beam (EB) Curing

EB-curable inks represent the gold standard for food-contact print applications where migration is the primary concern. The high-energy electron beam initiates polymerisation without requiring photoinitiators, eliminating a major migration source.

EB systems achieve near-complete cure throughout the ink film depth, resulting in extremely low extractable content. However, the capital cost of EB equipment (typically £2-4 million for an industrial system) restricts adoption to high-volume applications where the migration benefits justify the investment.

Migration Testing and Compliance Framework

Understanding Migration Pathways

Migration in printed food packaging occurs through three primary mechanisms:

Set-off migration occurs when printed and unprinted surfaces contact in roll or stack form. Ink components transfer from the printed surface to the food-contact surface, subsequently migrating into the food. This is particularly relevant for paper packaging where internal surfaces may contact external print during manufacturing and storage.

Gas-phase migration involves volatile ink components evaporating and re-condensing on food-contact surfaces or directly into the food. This mechanism is most significant for aromatic compounds and low molecular weight solvents, affecting dry and fatty foods particularly.

Direct migration occurs when printed surfaces directly contact food, either intentionally (overwrapped products) or unintentionally (handling during packaging operations).

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Set-Off Prevention

Functional barriers (coatings, laminated layers) can significantly reduce set-off migration. For paper packaging, an internal clay coating or PE lamination provides measurable barrier performance, though this must be validated through testing with specific ink systems.]

EU and UK Regulatory Framework

Food-contact materials in the UK and EU operate under Framework Regulation (EC) No 1935/2004, which establishes the principle that materials must not transfer constituents to food in quantities that could endanger human health or bring about unacceptable changes in food composition or organoleptic properties.

Unlike plastics, printing inks do not currently have specific EU harmonised legislation with a positive list of permitted substances. Instead, the industry operates under:

Swiss Ordinance RS 817.023.21 provides the most comprehensive positive list for printing ink components and serves as an industry reference throughout Europe.

Nestlé Guidance Note on Packaging Inks establishes concentration limits for various substance categories and is widely referenced in supply chain specifications.

EuPIA Guidance Documents (European Printing Ink Association) provide technical guidance on exclusion list substances, GMP, and migration testing protocols.

Migration Testing Protocols

Standard migration testing for printed food packaging follows the methodology established in EU Regulation 10/2011 for plastics, adapted for paper-based materials:

Overall migration testing measures total material transferred to food simulants under standardised time/temperature conditions. The limit is 10 mg/dm² of food-contact surface.

Specific migration testing quantifies individual substances of concern against established limits. Critical parameters for printing inks include photoinitiators (typically <50 ppb), primary aromatic amines (<10 ppb from azo pigments), and mineral oil hydrocarbons (MOSH/MOAH, with detection limits around 0.5 mg/kg food).

Food simulant selection must represent the food type:

  • Simulant A (ethanol 10%): aqueous foods
  • Simulant B (acetic acid 3%): acidic foods
  • Simulant D2 (vegetable oil or iso-octane): fatty foods
  • Poly(2,6-diphenyl-p-phenylene oxide), Tenax: dry foods

Print Quality Optimisation for Food Packaging

Achieving Consistent Colour Reproduction

Colour consistency in food packaging presents particular challenges due to the interaction between ink, substrate, and environmental factors. A systematic approach addresses the key variables:

Substrate qualification establishes baseline print performance for each paper grade. Key measurements include:

  • Brightness and whiteness (ISO 2470)
  • Surface roughness (Parker Print-Surf)
  • Porosity (Bendtsen or Gurley)
  • pH and extractable ions (affecting ink stability)

Ink standardisation ensures batch-to-batch consistency. Critical specifications include:

  • Viscosity at running temperature (±0.5 seconds Zahn cup)
  • pH (±0.2 units for water-based systems)
  • Colour strength (within spectrophotometric tolerance)

Process control parameters must be documented and maintained:

  • Anilox engagement (kiss contact to slight contact)
  • Impression pressure (minimum for complete ink transfer)
  • Web tension (consistent within ±5%)
  • Drying conditions (temperature, airflow, dwell time)

Dot Gain Management

Dot gain—the increase in halftone dot size from plate to print—is more pronounced on absorbent paper substrates than on films. Typical mechanical dot gain on uncoated paper ranges from 18-28% at the 50% tonal value, compared to 12-18% on coated papers.

Compensation strategies include:

Plate compensation curves reduce dot sizes on the plate to offset anticipated gain. Curve shapes are substrate-specific and must be calibrated for each paper/ink combination.

Anilox selection influences dot gain through ink film weight and cell geometry. Finer cell counts generally reduce gain but may compromise solid density.

HD/High Definition flexo processes using optimised plate-making technology (flat-top dots, optimised screening) can reduce dot gain by 5-10% compared to conventional approaches.

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Practical Dot Gain Target

For food packaging applications where regulatory text legibility is critical, target mechanical dot gain of 22% or less at 50% on uncoated substrates. This preserves sufficient contrast for 6-point regulatory text at 133 LPI screen ruling.]

Print Defect Prevention

Common print defects in flexographic food packaging operations include:

Pin-holing in solid areas results from contamination, inadequate ink film weight, or substrate surface irregularities. Prevention requires clean-room discipline, appropriate anilox selection, and substrate qualification.

Ghosting (density variation in the print direction) stems from inconsistent ink replenishment. Causes include insufficient anilox volume, excessive doctor blade pressure, or ink viscosity variations.

Picking occurs when the ink film tack exceeds the paper surface strength, removing fibres or coating particles. Reducing ink tack or selecting papers with higher surface strength addresses this issue.

Practical Implementation: Converting Operations

Pre-Press Considerations

Artwork preparation for food packaging requires attention to several compliance-critical elements:

Regulatory information positioning must ensure legibility after converting operations. Text must remain >6mm from any cut edge, fold line, or area subject to mechanical stress during converting.

Barcode specification follows GS1 guidelines, with particular attention to bar width reduction (BWR) compensation for dot gain on paper substrates. Typical BWR values range from 0.015-0.025mm for flexographic printing on paper.

Ink coverage optimisation balances visual impact against migration risk and material cost. Solid areas should be evaluated for functional necessity—often, tinted backgrounds can achieve similar visual effect at 40-60% coverage with significantly reduced ink consumption and migration potential.

Quality Assurance Protocols

A robust QA system for food-safe flexographic printing incorporates:

Incoming inspection of inks (viscosity, pH, colour, CoA verification) and substrates (dimensions, moisture, surface properties, CoC verification).

In-process monitoring including:

  • Density readings at defined intervals
  • Visual inspection for defects
  • Registration verification
  • Drying validation (rub test, blocking test)

Release testing appropriate to the application:

  • Migration testing (frequency based on risk assessment)
  • Organoleptic assessment for sensitive applications
  • Functional performance verification

"We've moved from end-of-run migration testing to statistical process control. By monitoring the variables that influence migration—cure energy, ink properties, process parameters—we can demonstrate compliance continuously rather than reactively."

— Quality Manager, Food Packaging Printer

Traceability Requirements

Food-contact regulations require full traceability throughout the supply chain. For printed packaging, this encompasses:

Ink batch traceability linking each production run to specific ink batches with documented compliance status.

Substrate traceability confirming food-contact suitability of base materials.

Process records documenting print conditions for each job (speeds, temperatures, operator, equipment).

Retention samples from each production run, stored under controlled conditions for the defined retention period (typically matching the food shelf life plus an appropriate margin).

[CTA: Ensure your printed food packaging meets all regulatory requirements. GML's technical team can review your current specifications and recommend optimised solutions for print quality and compliance. Contact us for a specification review.]

Conclusion: Balancing Competing Demands

Flexographic printing for food packaging requires continuous balancing of competing demands: print quality against migration risk, production efficiency against compliance documentation, cost optimisation against safety margins.

Success depends on understanding the interconnections between ink chemistry, substrate properties, process parameters, and regulatory requirements. There are genuine trade-offs—UV-curable inks offer superior print quality but require more rigorous migration management; water-based systems simplify compliance but may limit achievable quality on certain substrates.

The most effective approach treats print quality and food safety as complementary rather than competing objectives. Processes optimised for consistent ink transfer, complete drying or curing, and minimal waste also tend to deliver the best migration performance. Investment in process control and documentation pays dividends in both quality and compliance.

[CTA: Ready to optimise your flexographic printing for food packaging? Download our technical specification guide or contact GML's paper engineering team to discuss your specific requirements.]

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